Last updated on February 2018

Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia


Brief description of study

This is a randomised double-blinded placebo-controlled multi centre study in 98 patients with ACPA positive arthralgia. The study is composed of 2 arms with a 1:1 randomisation at baseline: Treatment phase will be 6 months. Group 1: Abatacept s.c. 125 mg weekly for 6 months vs. Group 2: Placebo s.c. for 6 months. After 6 months both groups will run into the follow up period for another 12 months up to month 18. Patients developing arthritis will be treated according to local guidelines.

Clinical Study Identifier: NCT02778906

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Johannes Strunk, Prof. Dr. med.

Krankenhaus Porz Am Rhein
Koeln, Germany
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Recruitment Status: Open


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