Last updated on June 2019

A Trial to Evaluate the Efficacy and Safety of MOR208 With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)


Brief description of study

The purpose of the study is to compare the safety and efficacy of MOR208 with BEN versus RTX with BEN in adult patients with relapsed of refractory DLBCL.

Detailed Study Description

This is a randomised, two-arm, multicentre, open-label phase II/III efficacy and safety study of MOR208 in combination with BEN versus RTX in combination with BEN given to adult patients who have relapsed after or are refractory to at least one but no more than three prior systemic therapies and have failed, or are not candidates for HDC and ASCT, and have thus exhausted their therapeutic options of demonstrated clinical benefit. At least one prior therapy line must have included a CD20-targeted therapy.

Clinical Study Identifier: NCT02763319

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Anaheim, CA United States
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Plainville, CT United States
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Bakersfield, CA United States
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Burbank, CA United States
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Rochester, MN United States
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Hattiesburg, MS United States
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Florham Park, NJ United States
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New York, NY United States
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Stony Brook, NY United States
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Columbus, OH United States
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Oklahoma City, OK United States
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Knoxville, TN United States
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Lubbock, TX United States
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Bedford Park, Australia
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South Brisbane, Australia
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Saint John's, NL Canada
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Greenfield Park, QC Canada
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Hradec Kralove, Czechia
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Chalon sur Saône, France
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Traunstein, Germany
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Budapest, Hungary
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Chalon sur Saône, France
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Szeged, Hungary
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Recruitment Status: Open


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