Last updated on March 2019

An Observational Study of Presentation Treatment Patterns and Outcomes in Multiple Myeloma Participants


Brief description of study

The purpose of this study is to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapeutic regimen chosen, and clinical outcomes in participants with newly diagnosed [ND] multiple myeloma (MM) and participants with relapsed/refractory [R/R] MM.

Detailed Study Description

This is a prospective, non-interventional, observational study. This study will look at contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapeutic regimen chosen, and clinical outcomes in participants with MM. Participants will not be asked to change their routine clinical treatment. Participants will have to complete patient reported outcomes (PROs) surveys during on-site routine office visits.

The study will enroll approximately 4200 participants. Participants will be assigned to one of the following cohorts based upon the diagnosis of MM:

  • ND MM within 3 months from initiation of treatment
  • R/R MM who have received 1 to 3 prior lines of therapy

This multi-center trial will be conducted worldwide. The overall time to participate in this study is up to 8 years. Participants will be evaluated and followed-up for a period of at least 5 years, until death, are lost to follow-up, or the end of the study, whichever comes first.

Clinical Study Identifier: NCT02761187

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CARTI Cancer Center
Little Rock, AR United States
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University of Arkansas For Medical Sciences
Little Rock, AR United States
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University of California San Diego
La Jolla, CA United States
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St Joseph Heritage Healthcare
Santa Rosa, CA United States
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Rocky Mountain Cancer Centers (Williams) - USOR
Denver, CO United States
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Poudre Valley Health System
Fort Collins, CO United States
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SCRI Florida Cancer Specialists East
Daytona Beach, FL United States
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SCRI Florida Cancer Specialists South
Fort Myers, FL United States
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SCRI Florida Cancer Specialists North
Saint Petersburg, FL United States
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Illinois Cancer Specialists (Niles) - USOR
Niles, IL United States
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East Jefferson General Hospital
Metairie, LA United States
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Central Maine Medical Center
Lewiston, ME United States
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Maryland Oncology Hematology (Columbia) - USOR
Columbia, MD United States
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Barbara Ann Karmanos Cancer Center
Detroit, MI United States
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Park Nicollet Institute
Saint Louis Park, MN United States
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Central Care Cancer Center
Bolivar, MO United States
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Kansas City VA Medical Center
Kansas City, MO United States
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Washington University in St. Louis
Saint Louis, MO United States
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Hunterdon Hematology Oncology
Flemington, NJ United States
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San Juan Oncology Associates
Farmington, NM United States
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Saint Francis Hospital
East Hills, NY United States
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Mount Sinai Medical Center
New York, NY United States
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Levine Cancer Center
Charlotte, NC United States
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University of Cincinnati
Cincinnati, OH United States
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Hematology Oncology Associates - USOR
Medford, OR United States
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Northwest Cancer Specialists (Broadway) - USOR
Portland, OR United States
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Fox Chase Cancer Center
Philadelphia, PA United States
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Greenville Health System Cancer Institute
Greenville, SC United States
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SCRI Tennessee Oncology Nashville
Nashville, TN United States
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Texas Oncology (Loop) - USOR
Amarillo, TX United States
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Texas Oncology (Loop) - USOR
Dallas, TX United States
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Texas Oncology (Loop) - USOR
El Paso, TX United States
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University of Texas MD Anderson Cancer Center
Houston, TX United States
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Texas Oncology (Loop) - USOR
Round Rock, TX United States
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Texas Oncology (Loop) - USOR
San Antonio, TX United States
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Yakima Valley Memorial Hospital North Star Lodge - USOR
Yakima, WA United States
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Berkeley Medical Center
Martinsburg, WV United States
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St Vincent Hospital
Green Bay, WI United States
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University of Wisconsin Carbone Cancer Center
Madison, WI United States
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Aurora Health Care, Aurora Cancer Care
Milwaukee, WI United States
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Grand Hopital de Charleroi asbl
Charleroi, Belgium
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Hopital de Jolimont
Haine-Saint-Paul, Belgium
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CHU UCL Namur asbl - Site Godinne
Yvoir, Belgium
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Unicamp Universidade Estadual de Campinas
Campinas, Brazil
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Centro de Pesquisas Oncologicas
Florianopolis, Brazil
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Hospital Das Clinicas Da Universidade Federal de Goias
Goiania, Brazil
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Universidade Federal Do Rio de Janeiro Hospital Universitario Clementino Fraga Filho
Rio de Janeiro, Brazil
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CEHON - Centro de Hematologia e Oncologia da Bahia Ltda
Salvador, Brazil
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Clinica Sao Germano
Sao Paulo, Brazil
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Hospital Israelita Albert Einstein
Sao Paulo, Brazil
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Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo
Sao Paulo, Brazil
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Peking Union Medical College Hospital
Beijing, China
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First Affiliated Hospital of Soochow University
Suzhou, China
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Fundacion Santa Fe de Bogota
Bogota, Colombia
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Fundacion Oftalmologica de Santander Foscal
Floridablanca, Colombia
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Hospital Pablo Tobon Uribe
Medellin, Colombia
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Oncomedica SA
Monteria, Colombia
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Centre Hospitalier Le Mans
Le Mans, France
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CHRU de Poitiers La Miletrie
Poitiers, France
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Centre Hospitalier Departemental de Vendee
Roche-sur-Yon, France
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CHU de Nancy-Hopital Brabois Adulte
Vandoeuvre-les-nancy, France
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Klinikum Chemnitz gGmbH
Chemnitz, Germany
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Gefos - Gesellschaft fur onkologische Studien mbH
Dortmund, Germany
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Universitatsklinikum Heidelberg
Heidelberg, Germany
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Internistisch Hamatologische und Internistische Praxis
Herrsching am Ammersee, Germany
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Institut fur Versorgungsforschung in der Onkologie GbR
Koblenz, Germany
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Universitatsmedizin der Johannes Gutenberg-Universitat Mainz
Mainz, Germany
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Mannheimer Onkologie Praxis
Mannheim, Germany
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OnkoNet Marburg GmbH
Marburg, Germany
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Onkologische Gemeinschaftspraxis Siegburg
Siegburg, Germany
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Universitatsklinikum Tubingen
Tubingen, Germany
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University Hospital of Alexandroupolis
Alexandroupoli, Greece
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Evangelismos General Hospital of Athens
Athens, Greece
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Alexandra Hospital
Athens, Greece
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University General Hospital of Ioannina
Ioannina, Greece
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University General Hospital of Larissa
Larisa, Greece
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University General Hospital of Patras
Patras, Greece
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HaEmek Medical Center
Afula, Israel
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Lady Davis Carmel Medical Center
Haifa, Israel
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Shaare Zedek Medical Center
Jerusalem, Israel
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Meir Medical Center
Kefar-Sava, Israel
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Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
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Assuta Medical Centers
Tel Aviv, Israel
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Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona-Umberto I G.M. Lancisi G. Salesi
Ancona, Italy
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Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi
Bologna, Italy
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Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele
Catania, Italy
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Azienda Ospedaliera Universitaria Careggi
Firenze, Italy
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Azienda Ospedaliera Universitaria Federico II
Napoli, Italy
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Azienda Ospedaliera Citta della Salute e della Scienza di Torino
Torino, Italy
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Nucleo Oncologico de Occidente S.C.
Guadalajara, Mexico
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Hematologica Alta Especialidad S.C.
Huixquilucan, Mexico
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Hospital Universitario Dr. Jose Eleuterio Gonzalez
Monterrey, Mexico
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Hospital Clinic de Barcelona
Barcelona, Spain
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Hospital Universitario Virgen de Las Nieves
Granada, Spain
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Complejo Asistencial Universitario de Leon
Leon, Spain
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Hospital Universitario 12 de Octubre
Madrid, Spain
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Hospital Universitario de Salamanca
Salamanca, Spain
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Hospital Universitari i Politecnic La Fe de Valencia
Valencia, Spain
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Kaohsiung Medical University Hospital
Kaohsiung, Taiwan
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Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital
Kaohsiung, Taiwan
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China Medical University Hospital
Taichung City, Taiwan
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National Cheng Kung University Hospital
Tainan, Taiwan
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National Taiwan University Hospital
Taipei, Taiwan
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Cukurova Universitesi Tip Fakultesi Balcali Hastanesi
Adana, Turkey
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Ankara University Medical Faculty Cebeci Hospital
Ankara, Turkey
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Akdeniz University Medical Faculty
Antalya, Turkey
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Johns Hopkins Medicine - Anadolu Saglik Merkezi
Gebze, Turkey
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Ege Universitesi Tip Fakultesi Hastanesi
Istanbul, Turkey
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Istanbul Universitesi Istanbul Tip Fakultesi Hastanesi
Istanbul, Turkey
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Dokuz Eylul University Medical Faculty
Izmir, Turkey
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Erciyes Universitesi Tip Fakultesi Hastanesi
Kayseri, Turkey
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Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
Samsun, Turkey
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Karadeniz Technical University Faculty of Medicine
Trabzon, Turkey
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Royal United Hospital
Bath, United Kingdom
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University Hospital Birmingham
Birmingham, United Kingdom
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Birmingham Heartlands Hospital
Birmingham, United Kingdom
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Royal Bournemouth Hospital
Bournemouth, United Kingdom
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Ninewells Hospital - PPDS
Dundee, United Kingdom
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Leicester Royal Infirmary
Leicester, United Kingdom
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Nottingham University Hospitals NHS Trust
Nottingham, United Kingdom
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The Royal Marsden NHS Foundation Trust
Sutton, United Kingdom
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Pinderfields General Hospital
Wakefield, United Kingdom
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George Washington University
Washington, WA United States
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Indiana University
Indianapolis, IN United States
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Veterans Affairs Pittsburgh Healthcare System
Pittsburgh, PA United States
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Peking University Peoples Hospital
Beijing, China
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The First Affiliated Hospital of College of Medicine, Zhejiang University
Hangzhou, China
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Centre Hospitalier de La Cote Basque
Bayonne, France
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Centre Hospitalier de Perigueux
Perigueux, France
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Azienda Policlinico Umberto I
Roma, Italy
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Azienda Sanitaria Universitaria Integrata di Udine
Udine, Italy
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Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mexico City, Mexico
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Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
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Chang Gung Medical Foundation Chiayi Chang Gung Memorial Hospital
Puzi, Taiwan
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Recruitment Status: Open


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