Last updated on May 2018

Study of ONO-4538 in Gastric Cancer


Brief description of study

The purpose of study is to evaluate the efficacy and safety of ONO-4538 with chemotherapy in unresectable advanced or recurrent gastric cancer (including esophagogastric junction cancer) not previously treated with the first-line therapy. Part 1 is intended to evaluate the tolerability, safety, and efficacy of ONO-4538 in combination with SOX therapy (Tegafur / gimeracil / oteracil potassium + Oxaliplatin) or CapeOX therapy (Capecitabine + Oxaliplatin). In part 2, the investigator or the subinvestigator will choose a chemotherapy (SOX or CapeOX therapy), taking into account the condition of each subject. Part 2 is planned to evaluate the efficacy and safety of ONO-4538 + chemotherapy in comparison with placebo + chemotherapy.

Clinical Study Identifier: NCT02746796

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Ono Pharmaceutical Co. Ltd Corporate ...

Aichi Clinical Site
Nagoya, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Aomori Clinical Site
Hirosaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Aomori Clinical Site
Misawa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Chiba Clinical Site
Funabashi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Chiba Clinical Site
Kamogawa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Chiba Clinical Site
Kashiwa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ehime Clinical Site1
Matsuyama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ehime Clinical Site2
Matsuyama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site
Iizuka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site1
Kitakyushu, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site2
Kitakyushu, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site
Kurume, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Gifu Clinical Site
Gifu-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Gifu Clinical Site
Ogaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Gumma Clinical Site
Maebashi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Gumma Clinical Site
Takasaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Gunma Clinical Site
Ota, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hiroshima Clinical Site
Kure, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hokkaido Clinical Site
Hakodate, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hokkaido Clinical Site1
Sapporo, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hokkaido Clinical Site2
Sapporo, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hokkaido Clinical Site3
Sapporo, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hyogo Clinical Site
Akashi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hyogo Clinical Site
Amagasaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hyogo Clinical Site
Kobe, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hyogo Clinical Site
Nishinomiya, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ibaraki Clinical Site
Higashiibaraki-gun, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ishikawa Clinical Site1
Kanazawa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ishikawa Clinical Site2
Kanazawa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Iwate Clinical Site
Morioka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kagawa Clinical Site
Kita-gun, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site
Isehara, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site
Kamakura, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site
Kawasaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site
Sagamihara, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site1
Yokohama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site2
Yokohama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kanagawa Clinical Site3
Yokohama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Miyagi Clinical Site
Natori, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Miyagi Clinical Site
Osaki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Nagano Clinical Site
Saku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Nara Clinical Site
Ikoma, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Okayama Clinical Site
Kurashiki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Izumi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Osakasayama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Sakai, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Suita, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Takatsuki, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site
Toyonaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Saitama Clinical Site
Hidaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Saitama Clinical Site
Kitaadachi-gun, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tochigi Clinical Site
Shimono, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tochigi Clinical Site
Shimotsuke, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tochigi Clinical Site
Utsunomiya, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Bunkyo-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Chuo-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Fuchu, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Minato-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Shinagawa-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site1
Shinjuku-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site2
Shinjuku-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Tachikawa, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tottori Clinical Site
Yonago, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Yamagata Clinical Site
Sakata, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Akita Clinical Site
Akita, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Chiba Clinical Site1
Chiba, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Chiba Clinical Site2
Chiba, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukui Clinical Site
Fukui, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site1
Fukuoka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site2
Fukuoka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site3
Fukuoka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukuoka Clinical Site4
Fukuoka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Fukushima Clinical Site
Fukushima, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hiroshima Clinical Site1
Hiroshima, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hiroshima Clinical Site2
Hiroshima, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Hiroshima Clinical Site3
Hiroshima, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kumamoto Clinical Site1
Kumamoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kumamoto Clinical Site2
Kumamoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kumamoto Clinical Site3
Kumamoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kyoto Clinical Site1
Kyoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kyoto Clinical Site2
Kyoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Kyoto Clinical Site3
Kyoto, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Niigata Clinical Site
Niigata, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Okayama Clinical Site
Okayama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site1
Osaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site2
Osaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site3
Osaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Osaka Clinical Site4
Osaka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Shizuoka Clinical Site
Shizuoka, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokushima Clinical Site
Tokushima, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Toyama Clinical Site
Toyama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Wakayama Clinical Site
Wakayama, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Yamagata Clinical Site
Yamagata, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Busan Clinical Site
Busan, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Daegu Clinical Site 1
Daegu, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Daegu Clinical Site 2
Daegu, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gwangju, Clinical Site
Gwangju, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site1
Gyeonggi-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site2
Gyeonggi-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site3
Gyeonggi-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site4
Gyeonggi-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site5
Gyeonggi-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeonggi-Do Clinical Site6
Gyeonggi-do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Incheon Clinical Site
Incheon, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Jeollabuk-do Clinical Site
Jeollabuk-do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Jeollanam-do Clinical Site
Jeollanam-do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seocho-gu Clinical Site
Seocho-gu, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 1
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 2
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 3
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 4
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 5
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site 6
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site7
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site8
Seoul, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Songpa-gu Clinical Site
Songpa-gu, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Ulsan Clinical Site
Ulsan, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Kaohsiung Clinical Site1
Kaohsiung, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Kaohsiung Clinical Site2
Kaohsiung, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

New Taipei Clinical Site 1
New Taipei, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

New taipei Clinical Site 2
New taipei, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taichung Clinical Site 1
Taichung, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taichung Clinical Site2
Taichung, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taichung Clinical Site3
Taichung, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Tainan Clinical Site1
Tainan, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Tainan Clinical Site2
Tainan, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taipei Clinical Site1
Taipei, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taipei Clinical Site2
Taipei, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Taoyuan Clinical Site
Taoyuan, Taiwan

Ono Pharmaceutical Co. Ltd Corporate ...

Hokkaido Clinical Site4
Sapporo-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Ibaraki Clinical Site
Tsuchiura-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Miyagi Clinical Site
Sendai-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Nara Clinical Site
Kashihara-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Shizuoka Clinical Site
Hamamatsu-shi, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Tokyo Clinical Site
Koto-ku, Japan

Ono Pharmaceutical Co. Ltd Corporate ...

Daejeon Clinical Site
Daejeon, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Gyeongnam Clinical Site
Gyeongnam, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Jeollabuk-Do Clinical Site
Jeollabuk-Do, Korea, Republic of

Ono Pharmaceutical Co. Ltd Corporate ...

Seoul Clinical Site9
Seoul, Korea, Republic of