Last updated on November 2018

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder


Brief description of study

To evaluate the efficacy and safety of AXS-05 relative to bupropion in subjects with treatment resistant major depressive disorder (MDD).

This is a randomized, double-blind, active-controlled, 12-week, two-period study consisting of an open-label, bupropion lead-in period, and a double-blind treatment period. The trial is being conducted in subjects with treatment resistant MDD.

Subjects will be considered to have treatment resistant MDD if they have had a historical inadequate response to 1 or 2 antidepressant treatments and a prospective inadequate response to treatment with bupropion during the open-label, lead-in period.

Clinical Study Identifier: NCT02741791

Find a site near you

Start Over

Cheryl Askew

Beverly Hills, CA United States
  Connect »

Cheryl Askew

Coral Springs, CA United States
  Connect »

Cheryl Askew

Garden Grove, CA United States
  Connect »

Cheryl Askew

Oceanside, CA United States
  Connect »

Cheryl Askew

Sherman Oaks, CA United States
  Connect »

Cheryl Askew

Temecula, CA United States
  Connect »

Cheryl Askew

Fort Myers, FL United States
  Connect »

Cheryl Askew

Gainesville, FL United States
  Connect »

Cheryl Askew

Jacksonville, FL United States
  Connect »

Cheryl Askew

Lakeland, FL United States
  Connect »

Cheryl Askew

Orlando, FL United States
  Connect »

Cheryl Askew

Atlanta, GA United States
  Connect »

Cheryl Askew

Skokie, IL United States
  Connect »

Cheryl Askew

Las Vegas, NV United States
  Connect »

Cheryl Askew

Berlin, NJ United States
  Connect »

Cheryl Askew

Cherry Hill, NJ United States
  Connect »

Cheryl Askew

Marlton, NJ United States
  Connect »

Cheryl Askew

Brooklyn, NY United States
  Connect »

Cheryl Askew

Jamaica, NY United States
  Connect »

Cheryl Askew

New York, NY United States
  Connect »

Cheryl Askew

Rochester, NY United States
  Connect »

Cheryl Askew

Canton, OH United States
  Connect »

Cheryl Askew

Dayton, OH United States
  Connect »

Cheryl Askew

Oklahoma City, OK United States
  Connect »

Cheryl Askew

Portland, OR United States
  Connect »

Cheryl Askew

Salem, OR United States
  Connect »

Cheryl Askew

Lincoln, RI United States
  Connect »

Cheryl Askew

Memphis, TN United States
  Connect »

Cheryl Askew

Dallas, TX United States
  Connect »

Cheryl Askew

Houston, TX United States
  Connect »

Cheryl Askew

Herndon, VA United States
  Connect »

Cheryl Askew

Bellevue, WA United States
  Connect »

Cheryl Askew

Seattle, WA United States
  Connect »

Cheryl Askew

Spokane, WA United States
  Connect »

Cheryl Askew

Redlands, CA United States
  Connect »

Cheryl Askew

Fort Lauderdale, FL United States
  Connect »

Cheryl Askew

Saint Louis, MO United States
  Connect »

Cheryl Askew

Allentown, PA United States
  Connect »

Cheryl Askew

Philadelphia, PA United States
  Connect »

Cheryl Askew

Charleston, SC United States
  Connect »

Cheryl Askew

Austin, TX United States
  Connect »

Cheryl Askew

San Antonio, TX United States
  Connect »

Cheryl Askew

Wichita Falls, TX United States
  Connect »

Cheryl Askew

Charlottesville, VA United States
  Connect »

Cheryl Askew

Phoenix, AZ United States
  Connect »

Cheryl Askew

Little Rock, AR United States
  Connect »

Cheryl Askew

Anaheim, CA United States
  Connect »

Cheryl Askew

Oakland, CA United States
  Connect »

Cheryl Askew

Panorama City, CA United States
  Connect »

Cheryl Askew

Riverside, CA United States
  Connect »

Cheryl Askew

San Diego, CA United States
  Connect »

Cheryl Askew

San Francisco, CA United States
  Connect »

Cheryl Askew

Upland, CA United States
  Connect »

Cheryl Askew

Colorado Springs, CO United States
  Connect »

Cheryl Askew

Cromwell, CT United States
  Connect »

Cheryl Askew

Washington, WA United States
  Connect »

Cheryl Askew

North Miami, FL United States
  Connect »

Cheryl Askew

Pensacola, FL United States
  Connect »

Cheryl Askew

Saint Petersburg, FL United States
  Connect »

Cheryl Askew

Boise, ID United States
  Connect »

Cheryl Askew

Shreveport, LA United States
  Connect »

Cheryl Askew

Baltimore, MD United States
  Connect »

Cheryl Askew

Weymouth, MA United States
  Connect »

Cheryl Askew

Saint Charles, MO United States
  Connect »

Cheryl Askew

Nashua, NH United States
  Connect »

Cheryl Askew

Princeton, NJ United States
  Connect »

Cheryl Askew

Toms River, NJ United States
  Connect »

Cheryl Askew

Albuquerque, NM United States
  Connect »

Cheryl Askew

Staten Island, NY United States
  Connect »

Cheryl Askew

Charlotte, NC United States
  Connect »

Cheryl Askew

Middleburg Heights, OH United States
  Connect »

Cheryl Askew

Media, PA United States
  Connect »

Cheryl Askew

Orem, UT United States
  Connect »

Cheryl Askew

Waukesha, WI United States
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.