Last updated on December 2019

EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injection


Brief description of study

Clinical and genetic evaluation of individuals treated with intravitreal aflibercept injection (Eylea) for neovascular age-related macular degeneration (wet AMD)

Detailed Study Description

Clinical and genetic assessment of treatment response in patients with age-related macular degeneration using intravitreal aflibercept injection. This study seeks to determine if different genetic polymorphisms of vascular endothelial growth factor A (VEGF-A) and HtrA serine peptidase 1(HTRA1) and other genes correlate to the response to intravitreal aflibercept injection therapy.

Clinical Study Identifier: NCT02689518

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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