Last updated on August 2018

Validation of DNA Methylation Biomarkers for Oral Cancer Detection


Brief description of study

The purpose of this study is to investigate the correlation between DNA methylation and the treatment and recurrence of oral cancer.

Detailed Study Description

In this study, investigators plan to recruit 40~50 patients who had, or currently has oral cancer. The study procedures are as below: - After the Informed Consent Form is signed, swab from the lesion site and normal site to obtain oral epithelial cells. - Collect tissue from the tumor site and the non-cancerous matched site from the surgery or the tissue bank. - Collect oral swab from the lesion site and the normal site when patients return to the clinic for a regular follow-up. Specimens will be collected for DNA methylation testing, and the results will be compared with patient's clinical diagnosis. It is expected that the relationship between DNA methylation, oral cancer, and the recurrence of oral cancer will be found.

Clinical Study Identifier: NCT02648789

Contact Investigators or Research Sites near you

Start Over

Cheng-Chieh Yang, DDS., Ph.D.

Taipei Veterans General Hospital
Taipei, Taiwan