Last updated on January 2017

The PRONTO Study a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis


Brief description of study

This is a global, multicenter, Phase 2b, randomized, double-blind, placebo-controlled, two-arm, parallel-group efficacy and safety study of NEOD001 as a single agent administered intravenously in adults with AL amyloidosis who had a hematologic response to previous treatment for their amyloidosis (e.g., chemotherapy, autologous stem cell transplant [ASCT]) and have persistent cardiac dysfunction.

Clinical Study Identifier: NCT02632786

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Michael Rosenzweig, MD

City of Hope
Duarte, CA United States
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Michaela Liedtke, MD

Stanford Cancer Institute (SCI)
Stanford, CA United States
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Tara Gregory, MD

Colorado Blood Cancer Institute
Denver, CO United States
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Taimur Sher, MD

Mayo Clinic
Jaksonville, FL United States
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Cara Rosenbaum, MD

University of Chicago Medicine
Chicago, IL United States
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Rafat Abonour, MD

Indiana University Simon Cancer Center
Indianapolis, IN United States
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Raymond Comenzo, MD

Tufts Medical Center
Boston, MA United States
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Vaishali Sanchorawala, MD

Boston University School of Medicine
Boston, MA United States
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Jeffrey Zonder, MD

Karmanos Cancer Institute
Detroit, MI United States
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Morie Gertz, MD

Mayo Clinic - Minnesota
Rochester, MN United States
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Heather Landau, MD

Memorial Sloan-Kettering Cancer Center
New York, NY United States
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Cristina Gasparetto, MD

Duke University Medical Center
Durham, NC United States
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Jason Valent, MD

The Cleveland Clinic
Cleveland, OH United States
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Stephen Heitner, MD

Oregon Health & Science University
Portland, OR United States
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Brendan Weiss, MD

Hospital of the University of Pennsylvania
Philadelphia, PA United States
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Stacey Goodman, MD

Vanderbilt University Medical Center
Nashville, TN United States
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Hans Lee, MD

University of Texas; MD Anderson Cancer Center
Houston, TX United States
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Edward Libby, MD

University of Washington/Seattle Cancer Care Alliance
Seattle, WA United States
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Anita D'Souza, MD

Froedtert & Medical College of Wisconsin, Cancer Center - Froedtert Hospital
Milwaukee, WI United States
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Fiona Kwow, MD

Westmead Hospital
Sydney, Australia
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Peter Molle, MD

The University of Queensland - Princess Alexandra Hospital (PAH)
Woolloongabba, Australia
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Simon Gibbs, MD

Eastern Health (Box Hill Hospital)
Box Hill, Australia
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Hermine Agis, MD

Medizinische Universit t Wien, Allgemeines Krankenhaus der Stadt Wien
Vienna, Austria
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Arnaud Jaccard, MD

H pital Dupuytren - CHU Limoges
Limoges, France
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Sylvain Choquet, MD

H pital Piti -Salp tri re
Paris, France
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Lionel Karlin, MD

Hopitaux Lyon Sud
Pierre-Benite Cedex, France
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Olivier Decaux, MD

CHU Rennes, Service de Medecine Interne
Rennes Cedex 2, France
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Axel Nogai, MD

Charite-Universitatsmedizin
Berlin, Germany
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Alexander Carpinteiro, MD

Universit tsklinikum Essen
Essen, Germany
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Timon Hansen, MD

Universitatsklinikum Hamburg-Eppendorf (UKE
Hamburg, Germany
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Stefan Schoenland, MD

Universitatsklinikum Heidelberg
Heidelberg, Germany
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Efstathios Kastritis, MD

Alexandra General Hospital of Athens
Athens, Greece
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Anargyros Symeonidis, MD

University Hospital of Patras
Patras, Greece
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Moshe Gatt, MD

Hadassah University Medical Center
Jerusalem, Israel
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Giampaolo Merlini, MD

Policlinica San Matteo
Pavia, Italy
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Joan Blade, MD

Hospital Clinic de Barcelona
Barcelona, Spain
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Isabel Krsnik, MD

Hospital Universitario Puerta de Hierro - Majadahonda
Majadahonda, Spain
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Guy Pratt, MD

Centre for Clinical Haematology
Birmingham, United Kingdom
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Ashutosh Wechalekar, MD

The Royal Free London NHS Foundation Trust - The Royal Free Hospital
London, United Kingdom
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Matthew Jenner, MD

Southampton General Hospital
Southampton, United Kingdom
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