Last updated on December 2018

A Study Evaluating Safety Pharmacokinetics and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)


Brief description of study

This first-in-human, open-label, multicenter, Phase Ia/Ib, adaptive, multiple ascending-dose study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary anti-tumor activity of RO6874281 as a single agent (Part A) or in combination with trastuzumab or cetuximab (Part B or C).

Clinical Study Identifier: NCT02627274

Contact Investigators or Research Sites near you

Start Over

Reference Study ID Number: BP29842 ...

University of Arizona Cancer Center
Tucson, AZ United States
  Connect »

Reference Study ID Number: BP29842 ...

UCSD - Moores Cancer Center
La Jolla, CA United States
  Connect »

Reference Study ID Number: BP29842 ...

University of Colorado Hospital - Anschutz Cancer Pavilion
Aurora, CO United States
  Connect »

Reference Study ID Number: BP29842 ...

Memorial Sloan Kettering
New York, NY United States
  Connect »

Reference Study ID Number: BP29842 ...

Centre Georges Francois Leclerc
Dijon, France
  Connect »

Reference Study ID Number: BP29842 ...

Institut Claudius Regaud; Departement Oncologie Medicale
Toulouse, France
  Connect »

Reference Study ID Number: BP29842 ...

Antoni Van Leeuwenhoek Ziekenhuis; Gastro-Enterologie
Amsterdam, Netherlands
  Connect »

Reference Study ID Number: BP29842 ...

Erasmus MC
Rotterdam, Netherlands
  Connect »

Reference Study ID Number: BP29842 ...

Clinica Universitaria de Navarra
Pamplona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital del Mar; Servicio de Oncologia
Barcelona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Univ Vall d'Hebron; Servicio de Oncologia
Barcelona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Universitario 12 de Octubre; Servicio de Oncologia
Madrid, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia
Valencia, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Leicester Royal Infirmary
Leicester, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Barts Health NHS Trust - St Bartholomew's Hospital
London, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Christie Hospital
Manchester, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Fondazione IRCCS Istituto Nazionale dei Tumori;S.S. Trattamento MedicoTumori dellaTesta e delCollo
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Istituto Europeo di Oncologia; Svil. Nuovi Farmaci per Terapie Innovative
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Azienda Socio Sanitaria Territoriale Niguarda (Ospedale Niguarda Ca' Granda); Oncologico -Onc.Falck
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Rigshospitalet; Onkologisk Klinik
København Ø, Denmark
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.