Last updated on July 2016

Probiotics on Immune Function and Intestinal Microbiota in Astronauts Under Closed Microgravity Environment

Brief description of study

Human immune function and intestinal microbiota are suggested to be altered within long-duration stay in space. Accumulated evidences on earth support that Lactobacillus casei strain Shirota (LcS) is a promising probiotic strain on improvement of immune function and intestinal microbiota. This study aims to investigate the impact of long-duration spaceflight as well as intake of LcS on the international space station (ISS), on immune system and intestinal microbiota in astronauts.

Clinical Study Identifier: NCT02618005

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Hiroshi Oshima, MD

Japan Aerospace Exploration Agency
Ibaraki, Japan
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Recruitment Status: Open

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