Last updated on January 2019

An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide Each Given With Radiation Therapy for Newly-diagnosed Patients With Glioblastoma (GBM a Malignant Brain Cancer)


Brief description of study

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-unmethylated (the MGMT gene is not altered by a chemical change). Patients will receive Nivolumab every two weeks in addition to radiation therapy, and then every four weeks. They will be compared to patients receiving standard therapy with temozolomide in addition to radiation therapy.

Clinical Study Identifier: NCT02617589

Find a site near you

Start Over

Cedars Sinai Medical Center

Los Angeles, CA United States
  Connect »

UCLA Neuro-Oncology Program

Los Angeles, CA United States
  Connect »

Sharp Memorial Hospital

San Diego, CA United States
  Connect »

Yale Cancer Center

New Haven, CT United States
  Connect »

Moffitt Cancer Center

Tampa, FL United States
  Connect »

The University Of Chicago

Chicago, IL United States
  Connect »

Norton Cancer Institute

Louisville, KY United States
  Connect »

Local Institution

Boston, MA United States
  Connect »

Henry Ford Health System

Detroit, MI United States
  Connect »

JFK Medical Center

Edison, NJ United States
  Connect »

Levine Cancer Institute

Charlotte, NC United States
  Connect »

Cleveland Clinic

Cleveland, OH United States
  Connect »

The Ohio State University

Columbus, OH United States
  Connect »

Local Institution

Oklahoma City, OK United States
  Connect »

Lehigh Valley Health Network

Allentown, PA United States
  Connect »

Thomas Jefferson University

Philadelphia, PA United States
  Connect »

Huntsman Cancer Institute

Salt Lake City, UT United States
  Connect »

Local Institution

Liverpool, Australia
  Connect »

Local Institution

Heidelberg, Australia
  Connect »

Uz Leuven

Leuven, Belgium
  Connect »

Local Institution

Copenhagen, Denmark
  Connect »

Local Institution

Lille Cedex, France
  Connect »

Local Institution

Paris cedex 13, France
  Connect »

Local Institution

Rennes Cedex, France
  Connect »

Local Institution

Vandoeuvre Les Nancy, France
  Connect »

Local Institution

Petach Tikva, Israel
  Connect »

Local Institution

Rozzano (milano), Italy
  Connect »

Local Institution

Hiroshima-Shi, Japan
  Connect »

Local Institution

Kanazawa-shi, Japan
  Connect »

Local Institution

Kagoshima-shi, Japan
  Connect »

Local Institution

Sagamihara-shi, Japan
  Connect »

Local Institution

Kumamoto-shi, Japan
  Connect »

Local Institution

Hirakata-shi, Japan
  Connect »

Local Institution

Yamagata-shi, Japan
  Connect »

NKI AVL

Amsterdam, Netherlands
  Connect »

Erasmus Mc

Rotterdam, Netherlands
  Connect »

Local Institution

Moscow, Russian Federation
  Connect »

Local Institution

Badalona-Barcelona, Spain
  Connect »

Local Institution

Santiago De Compostela, Spain
  Connect »

Royal Marsden Hospital

Sutton, United Kingdom
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.