Last updated on December 2018

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension

Brief description of study

The objective of this clinical trial is to compare the efficacy and safety of an initial triple oral treatment regimen (macitentan, tadalafil, selexipag) versus an initial dual oral treatment regimen (macitentan, tadalafil, placebo) in newly diagnosed, treatment-nave patients with pulmonary arterial hypertension.

Clinical Study Identifier: NCT02558231

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UCSD Health Sciences

La Jolla, CA United States
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UCLA Medical Center

Los Angeles, CA United States
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Cleveland Clinic Florida

Weston, FL United States
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Tufts Medical Center

Boston, MA United States
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The Christ Hospital

Cincinnati, OH United States
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UPMC Presbyterian

Pittsburgh, PA United States
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Houston Methodist Hospital

Houston, TX United States
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H pital Erasme

Brussels, Belgium
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Mayo Clinic Jacksonville

Jacksonville, FL United States
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Northwestern University

Chicago, IL United States
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University of New Mexico Hospital

New Orleans, LA United States
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The Alfred Hospital

Melbourne, Australia
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AKH Wien

Wien, Austria
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CHU de Bic tre

Le Kremlin-Bicêtre, France
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VUmc Amsterdam

Amsterdam, Netherlands
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Recruitment Status: Open

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