Last updated on November 2019

Trial of Afatinib in Pediatric Tumours


Brief description of study

Open-label, dose escalation, monotherapy, basket trial with biomarker specific MTD expansion cohort/Phase II part.

The trial will consist of 2 parts:

  1. Dose finding part to determine the MTD
  2. Biomarker specific MTD expansion cohort/Phase II part to assess clinical anti-tumour activity in included tumour types

Clinical Study Identifier: NCT02372006

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