Last updated on March 2018

A clinical research study for the treatment of Rheumatoid Arthritis, Ankylosing spondylitis


Brief description of study

The objectives of the study are:

Primary objective:

  • To determine the safety and tolerability of medical imaging with 99mTc-rhAnnexin V-128

Secondary objectives:

  • To determine the biodistribution, pharmacokinetics and radiation dosimetry of 99mTc-rhAnnexin V-128
  • To demonstrate the time-dependant distribution and localization of 99mTc-rhAnnexin V-128 both in RA and AS patients
  • To determine ability of early imaging with 99mTc-rhAnnexin V-128 to evaluate the presence of lesions before and after short term treatment of either RA or AS patients.

Study hypothesis:

99mTc-rhAnnexin V-128 could be used as an adjunct for the diagnosis of early stage rheumatoid arthritis and ankylosing spondylitis and for the assessment of response to treatment of these diseases.

Clinical Study Identifier: NCT02328027

Contact Investigators or Research Sites near you

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Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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