Last updated on April 2019

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Acute Coronary Syndrome
  • Age: Between 18 - 99 Years
  • Gender: Male or Female

Inclusion Criteria:

Patients (18 years of age) with a working diagnosis of NSTEMI and treatment with an OAP agent (ticagrelor, clopidogrel, or prasugrel) either in the ED, or in any case within the timeframe that emergency physicians consider to be "upstream"- i.e., within the first 72 hours of care and at least 4 hours before diagnostic angiography. In addition, only those patients who undergo a diagnostic coronary angiography within 72 hours of ED arrival will be eligible for UPSTREAM.

Exclusion Criteria:

  1. Life expectancy less than 90 days in opinion of treating clinician;
  2. Not undergoing diagnostic angiography within 72 hours of ED arrival;
  3. Refusal of consent; or
  4. Unlikely to comply with follow-up by telephone.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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