Last updated on August 2015

APIC-CF Therapy for Mild to Moderate Osteoarthritis of the Knee

Brief description of study

The mechanism of Osteoarthritis (OA) is complex, however the investigators know that cartilage breakdown follows changes in certain cells in the cartilage called chondrocytes, leading to proteases that break down cartilage. There is a protein in the human blood called alpha-2-macroglobulin that can trap these proteases and prevent the breakdown of cartilage. Cytonics developed a device that use the patient's own blood to remove all cells and concentrate alpha-2-macroglobulin to be injected in the painful knee due to osteoarthritis.

Clinical Study Identifier: NCT02210468

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IRC Clinical

Townsend, MD United States
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Recruitment Status: Open

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