Last updated on January 2016

Observational Study to Investigate the Effectiveness of Eprosartan on Pulse Pressure (Teveten_MS)

Brief description of study

The study is to identify the effectiveness of Eprosartan on pulse pressure in hypertensive patients with metabolic syndrome -Definition of pulse pressure (PP): Difference between systolic and diastolic blood pressure produced one heart beat.

Detailed Study Description

Primary Objective -To assess the changes of pulse pressure at 12 weeks Secondary Objectives - To assess the changes of pulse pressure at 4, 24 weeks - To assess the changes of systolic blood pressure and diastolic blood pressure at each visit - Percentage of responder rate* at each visit and time to get normalized BP from enrollment - Responder rate at last visit - To assess IIEF-5 (5-item Version of the International Index of Erectile Function) score at enrollment and 24 weeks (percentage of patients with ED according to IIEF-5, Changes of IIEF-5 domains) - Percentage of patients with erectile dysfunction (ED) according to IIEF-5 and changes of PP in subgroup (age 65, body mass index (BMI) 23, diabetes mellitus, dyslipidemia, benign prostate hypertrophy) - Analysis of correlation between ED and concomitant disease and concomitant medications in patients who received Eprosartan - Score changes of Framingham 10-year Coronary Heart Disease (CHD) risk at 1st visit, 4th visit - Percentages of Eprosartan monotherapy and multiple antihypertensive therapies at enrollment and last visit - Reason for treatment discontinuation (Inadequate BP control, adverse events, others) - Adverse events - Responder rate: SBP <140mmHg and DBP <90mmHg (SBP <140mmHg and DBP <85mmHg for patients with diabetes mellitus)

Clinical Study Identifier: NCT02024100

Find a site near you

Start Over

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.