Last updated on September 2018

A Phase 3 clinical study for patients with Mesothelioma


Brief description of study

This is a phase II/III confirmatory study designed to evaluate the safety and efficacy of nintedanib (BIBF 1120) in combination + (pemetrexed / cisplatin) followed by nintedanib (BIBF 1120) versus placebo + pemetrexed / cisplatin followed by placebo for the treatment of patients with unresectable malignant pleural mesothelioma.

Clinical Study Identifier: NCT01907100

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University of Alabama at Birmingham
Birmingham, AL United States

Comprehensive Cancer Centers of Nevada- Peak Office
Henderson, NV United States

University of Pittsburgh Medical Center
Pittsburgh, PA United States

Greenville Health System
Greenville, SC United States

The University of Texas MD Anderson Cancer Center
Houston, TX United States

Texas Oncology - McAllen
McAllen, TX United States

Texas Oncology-San Antonio Northeast
San Antonio, TX United States

Cancer Care Northwest Centers, PS
Spokane Valley, WA United States

Cl nica Universitaria Reina Fabiola
Ciudad de Cordoba, Argentina

Northern Cancer Institute
St Leonards, Australia

Calvary Mater Newcastle Hospital
Waratah, Australia

The Prince Charles Hospital
Chermside, Australia

Mater Cancer Care Centre
South Brisbane, Australia

Box Hill Hospital
Box Hill, Australia

Peninsula Haematology & Oncology
Frankston, Australia

Austin Health
Heidelberg, Australia

Border Onclogy Research
Wodonga, Australia

Sir Charles Gairdner Hospital
Nedlands, Australia

Perth Oncology
Perth, Australia

LKH Leoben
Leoben, Austria

Klinikum Wels - Grieskirchen GmbH
Wels, Austria

Brussels - UNIV St-Luc
Bruxelles, Belgium

Edegem - UNIV UZ Antwerpen
Edegem, Belgium

UNIV UZ Gent
Gent, Belgium

UZ Leuven
Leuven, Belgium

QEII Health Sciences Centre (Dalhousie University)
Halifax, NS Canada

IUCPQ (Laval University)
Quebec, QC Canada

Centro Internacional de Estudios Cl nicos - CIEC
Recoleta, Chile

Orlandi Oncologia
Vitacura, Chile

University Clinic for Pulmonary Diseases
Zagreb, Croatia

University Hospital Brno
Brno, Czechia

University Hospital Olomouc
Olomouc, Czechia

Clinical Research Center Alexandria
Alexandria, Egypt

Medical Research Institute
Alexandria, Egypt

National Cancer Institute, Cairo University
Cairo, Egypt

Nasser Institute
Cairo, Egypt

HOP Morvan
Brest, France

HOP C te de Nacre
Caen, France

HOP Calmette
Lille, France

HOP Nord
Marseille, France

HOP Larrey
Toulouse, France

INS Gustave Roussy
Villejuif, France

Vivantes Netzwerk f r Gesundheit GmbH
Berlin, Germany

HELIOS Klinikum Emil von Behring GmbH
Berlin, Germany

Thoraxklinik-Heidelberg gGmbH am Universit tsklinikum Heidelberg
Heidelberg, Germany

Universit tsklinikum des Saarlandes
Homburg/Saar, Germany

Soroka Univ. Medical Center
Beer Sheva, Israel

Rambam Medical Center
Haifa, Israel

Meir Medical Center
Kfar-Saba, Israel

Rabin Medical Center Beilinson
Petach Tikva, Israel

Sourasky Medical Center
Tel-Aviv, Israel

Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo
Alessandria, Italy

Humanitas Gavazzeni
Bergamo, Italy

Istituto Nazionale per la Ricerca sul Cancro
Genova, Italy

A.O. San Gerardo di Monza
Monza, Italy

Azienda Sanitaria Ospedale S. Luigi Gonzaga
Orbassano (TO), Italy

A.O. S.Maria degli Angeli
Pordenone, Italy

A.O.U. Senese Policlinico Santa Maria alle Scotte
Siena, Italy

Ospedale S. Giuseppe Moscati
Statte (TA), Italy

University Hospital of Occupational and Environmental Health
Fukuoka, Kitakyushu, Japan

Hyogo Prefectural Amagasaki General Medical Center
Hyogo, Amagasaki, Japan

Hyogo College of Medicine Hospital
Hyogo, Nishinomiya, Japan

Yokosuka Kyosai Hospital
Kanagawa , Yokosuka, Japan

Japan Labour Health and Safety Organization Okayama Rosai Hospital
Okayama, Okayama, Japan

Kindai University Hospital
Osaka, OsakaSayama, Japan

Otemae Hospital
Osaka, Osaka, Japan

Juntendo University Hospital
Tokyo, Bunkyo-ku, Japan

Centro Oncologico de Chihuahua
Chihuahua, Mexico

Instituto Nacional de Cancerologia
Mexico, Mexico

Centro Oncologico Estatal ISSEMYM
Toluca, Mexico

Medisch Spectrum Twente
Enschede, Netherlands

Zuyderland Medisch Centrum
Heerlen, Netherlands

Erasmus Medisch Centrum
Rotterdam, Netherlands

St. Olavs Hospital, Universitetssykehuset i Trondheim
Trondheim, Norway

University Clinical Center, Gdansk
Gdansk, Poland

Clin. Hosp. of Univ. of Med. Sciences
Poznan, Poland

Wielkopolski Center Pulmonology+Tuberculosis P-III, Poznan
Poznan, Poland

Oncol Centre M Sklodowska-Curie, Dept of Lung & Chest Cancer
Warsaw, Poland

Centro Hospitalar Lisboa Norte Hospital Pulido Valente
Lisboa, Portugal

Hospital CUF Porto
Porto, Portugal

FGBUZ "Chelyabinsk Reg. Oncology Dispensary";Chemotherpy Dep
Chelyabinsk, Russian Federation

Republic Clinical Oncology Dispensary, Dept. Chemotherapy
Kazan, Russian Federation

First Pavlov State Medical University Saint Petersburg
Saint-Petersburg, Russian Federation

Republican Clinical Oncology Center Ufa
Ufa, Russian Federation

Wilgers Oncology Centre
Pretoria, South Africa

Hospital Universitario de Cruces
Barakaldo (Vizcaya), Spain

Hospital Vall d'Hebron
Barcelona, Spain

Hospital Cl nic de Barcelona
Barcelona, Spain

Hospital Universitario Donostia
Donostia (Gipuzkoa), Spain

Hospital Duran i Reynals
L'Hospitalet de Llobregat, Spain

Hospital Ram n y Cajal
Madrid, Spain

CS Parc Taul
Sabadell (Barcelona), Spain

Hospital Virgen del Roc o
Sevilla, Spain

Hospital Cl nico de Valencia
Valencia, Spain

Karolinska Univ. sjukhuset
Stockholm, Sweden

Akademiska sjukhuset
Uppsala, Sweden

Eskisehir Osmangazi ni. Sag. Uygulama ve Arastirma Has.
Eskisehir, Turkey

Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi
Istanbul, Turkey

Dr.Suat Seren EAH
Izmir, Turkey

Leicester Royal Infirmary
Leicester, United Kingdom

University of California San Francisco
San Francisco, CA United States

Univ.-Klinik f. Innere Medizin I, Onkologie, Wien
Wien, Austria

AZ Sint-Maarten
Mechelen, Belgium

Health Sciences North
Sudbury, ON Canada

Princess Margaret Cancer Centre
Toronto, ON Canada

Clinical Hospital Osijek
Osijek, Croatia

CLI Bordeaux Nord Aquitaine
Bordeaux, France

HOP HIA Saint-Anne
Toulon, France

Oslo Universitetssykehus HF, Radiumhospitalet
Oslo, Norway

FSBI "N.N. Petrov National Medical Research Center of Oncology" of MoH of RF
Saint-Petersburg, Russian Federation

Hospital Virgen de la Victoria
Malaga, Spain

Western General Hospital
Edinburgh, United Kingdom

Beatson West of Scotland Cancer Centre
Glasgow, United Kingdom

Guy's Hospital
London, United Kingdom

The Royal Marsden Hospital
London, United Kingdom

The Royal Marsden Hospital
Sutton, United Kingdom

Wythenshawe Hospital
Wythenshawe, United Kingdom

Rocky Mountain Cancer Centers
Littleton, CO United States

Sanatorio G emes
Ciudad Autónoma de Bs As, Argentina

Instituto Medico Especializado Alexander Fleming
Ciudad Autónoma de Bs As, Argentina

Rigshospitalet, K benhavn, Onkologisk afd
Købenahvn Ø, Denmark

HOP Lyon Sud
Pierre-Bénite, France

Evangelische Lungenklinik Berlin
Berlin, Germany

Klinik Schillerh he GmbH
Gerlingen, Germany

Pneumologisches Forschungsinstitut an der LungenClinic Grosshansdorf GmbH
Großhansdorf, Germany

Klinik, L wenstein
Löwenstein, Germany

Sahlgrenska US, G teborg
Göteborg, Sweden

Universitetssjukhuset, Link ping
Linköping, Sweden

Sk nes universitetssjukhus, Lund
Lund, Sweden

Recruitment Status: Closed


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