Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis

  • participants needed
  • sponsor
    Ministry of Science and Technology of the People´s Republic of China
Updated on 7 November 2020


The purpose of this study is to determine whether atorvastatin, aggressive lifestyle intervention, and their interaction are effective in delaying the progress of pre-clinical atherosclerosis.


Primary prevention of atherosclerotic disease remains a big challenge. Currently, it is not clear how to treat those subjects with evidence of pre-clinical atherosclerosis but without obvious conventional risk factors. This randomized, placebo controlled, double blind study is to evaluate the effect of Atorvastatin 10 mg daily, therapeutic lifestyle change, and their combination, on the progression of CIMT in those with higher baseline CIMT value but are not belong to 'high risk' category, according to the conventional risk factors.

Condition Atherosclerosis
Treatment Atorvastatin, Aggressive lifestyle intervention
Clinical Study IdentifierNCT00723320
SponsorMinistry of Science and Technology of the People´s Republic of China
Last Modified on7 November 2020


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