Last updated on July 2008

Effect of Losartan on Chronic Obstructive Pulmonary Disease (COPD)

Brief description of study

Losartan, an angiotensin receptor blocker, has been effective in preventing the development of emphysema and lung inflammation in animal models of COPD. Moreover, there is epidemiologic evidence that suggests that this drug may be effective in reducing COPD morbidity and mortality. This study will provide treatment with either losartan or placebo for a period of 12 months to determine whether there is progression of COPD as measured by high-resolution CT scans, lung function, or blood tests for inflammation.

Clinical Study Identifier: NCT00720044

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Johns Hopkins Hospital

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