Last updated on December 2010

Management of Patients With Alpha-1 Antitrypsin Deficiency Associated Emphysema

Brief description of study

The aim of this study is to describe the natural history of patients with alpha-1 antitrypsin associated emphysema and to figure out associated prognostic factors.

Detailed Study Description

All patients who suffer from this disease are followed every 6 months during a 5 years period. FEV1 decline is the primary endpoint. Quality of life assessed using the Saint George's Respiratory Questionary is recorded too.

Clinical Study Identifier: NCT00700934

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Gabriel Thabut, MD

Departement d' pid miologie, H pital Bichat
Paris, France
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