Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

  • End date
    Jun 24, 2030
  • participants needed
  • sponsor
    University of Southern California
Updated on 24 May 2022
sleep nasendoscopy


Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

Condition Sleep Apnea, Obstructive
Treatment Propofol sedation
Clinical Study IdentifierNCT00695214
SponsorUniversity of Southern California
Last Modified on24 May 2022


Yes No Not Sure

Inclusion Criteria

Adult patients with OSA considering surgical treatment

Exclusion Criteria

Pregnant women
Patients unable to provide informed consent in English themselves
Allergy to propofol, soybean oil, egg lecithin or glycerol
Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)
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