Last updated on April 2009

Dose-Reduced Versus Standard Conditioning Prior Allo SCT for MDS/sAML Patients

Brief description of study

The present study is a multicenter, prospective phase III-study comparing dose-reduced versus standard conditioning followed by allogeneic stem cell transplantation from related or unrelated donors in patients with MDS or secondary AML. The hypothesis is that dose-reduced conditioning will reduce the non-relapse mortality from 40% to 20% at one year after allogeneic stem cell transplantation.

Clinical Study Identifier: NCT00682396

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SPb State I. Pavlov Medical University

St. Petersburg, Russian Federation
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