Last updated on September 2014

Clinical Trial of Integrated Treatment for Pain and Opioid Dependence

Brief description of study

This study is designed to develop an effective psychotherapy for chronic pain and opioid dependence.

Detailed Study Description

This study aims to develop a novel manualized intervention using tailored cognitive-behavioral treatment (CBT) and buprenorphine medication to effectively treat the co-occurring disorders of non-malignant pain and opioid dependence (POD). Specific Aims: 1. To conduct a pre-pilot phase with 16 patients with POD receiving buprenorphine maintenance treatment (BMT). In the pre-pilot phase, we will also explore the effects of different daily buprenorphine dosages on pain and opiate use. 2. To conduct a pilot randomized, clinical trial to obtain data regarding the feasibility, acceptability and efficacy (compared to Physician Management(PM) only) of manual-guided CBT or Educational Counseling (EC) for patients with POD treated with BMT (N=75).

Clinical Study Identifier: NCT00634803

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Methadone Research Unit

New Haven, CT United States
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