Study of Apatinib as an Inhibitor of Tumor Angiogenesis
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- STATUS
- Recruiting
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- participants needed
- 18
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- sponsor
- Fudan University
Summary
Apatinib is a tyrosin-inhibitor agent targeting at vascular endothelial growth factor receptor (VEGFR), so it can inhibit tumor angiogenesis. This phase I study aims to determine the drug's toxicity and to find a dose level to be used in a phase II study in solid tumor patients.
Description
Apatinib is a tyrosin-inhibitor agent targeting at VEGFR (vasoendothelial growth factor receptor) to inhibit tumor angiogenesis. The anti-angiogenesis effect of apatinib has been viewed in preclinical tests (see protocol). This phase I clinical study is going to evaluate its toxicity and to find an appropriate dose level to be used in a phase II study in heavily treated solid tumor patients.
Details
| Condition | Cancer |
|---|---|
| Treatment | apatinib |
| Clinical Study Identifier | NCT00633490 |
| Sponsor | Fudan University |
| Last Modified on | 7 November 2020 |
Eligibility
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