Last updated on April 2019

Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: alpha-1-Antitrypsin deficiency | LIVER DISEASE | Alagille Syndrome
  • Age: - 25 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Children and young adults diagnosed with one of the four cholestatic diseases from birth through 25 years old.
  2. Siblings of participants with alpha-1-antitrypsin deficiency, who themselves have alpha-1-antitrypsin deficiency of liver disease.
  3. Both genders, all races and ethnic groups
  4. Participant meets the enrollment criteria for one of the four cholestatic liver diseases

Exclusion Criteria:

  1. Inability to comply with the longitudinal follow-up described below, or
  2. Failure of a family/patient to sign the informed consent document or the HIPAA medical record release form.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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