Last updated on June 2008

Atorvastatin for the Treatment of Retinal Vein Occlusion

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Thrombosis | Branch Retinal Vein Occlusion | Retinal Vein Occlusion | Central Retinal Vein Occlusion | Retinal Vein Thrombosis
  • Age: Between 40 - 100 Years
  • Gender: Male or Female
  • Other:
    Adults aged 40 years and older
    Diagnosed with CRVO or BRVO
    Visual acuity of 20/40 or worse in the affected eye
    Onset of current symptoms of loss of vision within the past 60 days
    Ability to understand spoken English

You may not be eligible for this study if the following are true:

  • Current use of a statin or fibrate medication
    Known cardiovascular disease or revascularization, including coronary artery disease
    (myocardial infarction or angina), stroke or peripheral artery occlusion
    Known diabetes mellitus
    Known liver disease
    Serum low-density lipoprotein cholesterol (LDL-C) > 5.0 mmol/L
    Baseline serum triglycerides > 6.0 mmol/L
    Serum ALT above 115 U/L (i.e., 2.5 x upper limit of normal)
    Baseline serum creatinine > 250 µmol/L
    Ocular surgery within the past 90 days
    Planned ocular or cataract surgery within the study period
    Known retinal disease: age-related macular degeneration, retinal detachment or
    macular hole, or past history of vein occlusion
    Women who are pregnant or who are breastfeeding
    Participation in another clinical trial concurrently or within 30 days prior to
    Known allergy to fluorescein dye
    Current use of cyclosporine medication.
    Current use of an HIV protease inhibitor medication.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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