Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis

  • participants needed
  • sponsor
    University of Cologne
Updated on 22 January 2022
cognitive therapy
schizoaffective disorder
psychotic symptoms
delusional disorder


In the last decade cognitive behavioural therapy (CBT) approaches for patients with schizophrenia have been developed, which where especially designed to reduce severity of positive symptoms, readmission rates, treatment non-compliance and disability. Although CBT addresses the key problems of early onset psychoses (EOP)treatment and first evaluations of CBT in adults with schizophrenia are promising, no experience with CBT in adolescents with EOP are available. Therefore the present study is conducted to develop a modified CBT (mCBT) for adolescents with EOP, to explore its acceptance and feasibility and to provide data for a realistic estimation of achievable effect size. Patients are randomized to receive either mCBT+TAU or TAU over a 9 month period. mCBT is an individual outpatient treatment of 20 session and 5 psychoeducational sessions with parents. Follow-ups for two years every 6 months are planned.

Condition Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder, Schizophreniform Disorder
Treatment modified cognitive behavioural therapy (mCBT)
Clinical Study IdentifierNCT00465920
SponsorUniversity of Cologne
Last Modified on22 January 2022

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