Last updated on October 2010

Study of Patients With Cancer or Precancerous Conditions

Brief description of study

RATIONALE: Following the course of disease in patients with cancer or precancerous conditions who are receiving standard care may help the study of cancer in the future. PURPOSE: This natural history study is looking at the course of disease in patients with cancer or precancerous conditions.

Detailed Study Description

OBJECTIVES: - To follow and evaluate patients, longitudinally with cancer or precancerous conditions referred to the NIH Clinical Center Pediatric Oncology Branch who present with disease manifestations that lend themselves to clinical evaluation and are of unique scientific importance. - To allow, when clinically indicated, patients to receive standard care therapies. OUTLINE: Patients are evaluated at least every 3-6 months for up to 3 years and receive standard care as prescribed. Demographic information, histology, pathologic findings, and laboratory and imaging parameters are collected during that time. Tissue specimens may be collected. Patients undergo periodic diagnostic x-rays and/or nuclear medicine scans. Previous medical care data will be obtained and entered into a database. PROJECTED ACCRUAL: A total of 250 patients will be accrued for this study.

Clinical Study Identifier: NCT00445536

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Recruitment Status: Open

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