Study of Optimal Treatment Plan in Hypertensives With Anti-AT1-Receptor Autoantibody
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- STATUS
- Recruiting
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- participants needed
- 600
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- sponsor
- Huazhong University of Science and Technology
Summary
The autoantibodies against AT1 receptor (ATR-AA), behaving like an agonist were detected in patients with hypertension. ATR-AA which can blocked by ARB may play a role in the pathogenesis of hypertension. The present study is to explore whether AT1 receptor blocker has superior anti-hypertensive effect in patients with positive ATR-AA hypertension. Patients with 2 grade hypertension were recruited and ATR-AA was assayed by ELISA. A study was carried out and the efficacy of anti-hypertension was compared between candesartan cilexetil and ACE inhibitor imidapril.
Details
| Condition | Hypertension |
|---|---|
| Treatment | candesartan cilexetil |
| Clinical Study Identifier | NCT00360763 |
| Sponsor | Huazhong University of Science and Technology |
| Last Modified on | 7 November 2020 |
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