Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degeneration

  • STATUS
    Recruiting
  • participants needed
    25
  • sponsor
    Asociación para Evitar la Ceguera en México
Updated on 7 November 2020
photodynamic therapy
bevacizumab
corrected visual acuity
verteporfin
age-related macular degeneration

Summary

The purpose of this study is to determine if of combination therapy of intravitreal bevacizumab 4 days after the application of photodynamic therapy could improve the visual outcomes of patients with neovascular age related macular degeneration.

Description

The neovascular age related macular degeneration(AMD) is a important cause of legal blindness in adults older than 50 years. Currently the treatment is photodynamic therapy that offer stabilization and limited visual improvement after 2 years of therapy. Bevacizumab has been reported effective used as intravenous injection for AMD. But serious side effects have been reported with the use of this drug in oncologic patients. The intravitreal use has been reported in limited case reports and safety and efficacy should be determined. The purpose of this study is efficacy and safety of 2.5 mg intravitreal of bevacizumab for AMD 4 days after photodynamic therapy with verteporfin

Details
Condition age-related macular degeneration
Treatment bevacizumab intravitreal injection, verteporfin photodynamic therapy
Clinical Study IdentifierNCT00347399
SponsorAsociación para Evitar la Ceguera en México
Last Modified on7 November 2020

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