The Effects of Sufentanil vs. Remifentanil in Total Intravenous Anesthesia With Remimazolam on Postoperative Pain

  • End date
    Jun 6, 2025
  • participants needed
  • sponsor
    Yonsei University
Updated on 6 April 2023


In this study, the investigators evaluate the effect of total intravenous anesthesia using sufentanil-remimazolam and remifentanil-remimazolam on postoperative pain in patients undergoing laparoscopic gastrectomy.

Condition Stomach Neoplasms
Treatment sufentanil-remimazolam group, remifentanil-remimazolam group
Clinical Study IdentifierNCT05785234
SponsorYonsei University
Last Modified on6 April 2023


Yes No Not Sure

Inclusion Criteria

20years or older
Scheduled for laparoscopic-assisted gastrectomy
American Society of Anesthesiologists(ASA) physical status I and III

Exclusion Criteria

Emergency operation
Patients with a history of severe hypersensitivity reaction to dextran 40
Patients who cannot use patient controlled analgesia(PCA)
Patients with morbid obesity [body mass index (BMI) >35 kg/m2]
Patients with history of uncontrolled hypertension (diastolic BP >110mmHg) or DM
Patients with history of heart failure (unstable angina, congestive heart failure)
Patients with history of liver failure, renal failure, allergic to medicine
Patients with history of cerebrovascular disease (cerebral hemorrhage, cerebral ischemia)
Patients with history of uncontrolled psychiatric disease (PTSD, anxiety, depression)
Patients with obstructive sleep apnea
Patients who cannot read the consent form (examples: Illiterate, foreigner)
Patients who withdraw the consent
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