Behavioral Predictors of Illness Progression in Adolescent Depression

  • End date
    Jan 31, 2025
  • sponsor
Updated on 13 March 2023


This study looks at what predicts depression in adolescents. 


We follow teens over three years with two visits at baseline, two follow-up visits at 12 months, and one final visit at 24 months. The visits consist of a clinical interview (either in-person or remote) and an MRI scan and blood draw at Mount Sinai Hospital.

Compensation up to $400 provided for completing both the clinical and scan visits. 

Condition Depression (Adolescent), Depression (Major/Severe)
Clinical Study IdentifierTX310378
Last Modified on13 March 2023


Yes No Not Sure

Inclusion Criteria

Psychotropic-medication free for at least a month
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Exclusion Criteria

Active suicidal ideations
MRI contraindications (e.g. pregnancy, metal-ink tattoos, piercings, etc.)
Positive urine toxicology test except for cannabis
Immune-affecting medications or herbal supplements taken (e.g. steroids, non-steroidal anti-inflammatory drugs, omega-3 fatty acids)
Neurological and medical illness (e.g. epilepsy, nerve conduction disorders, and all inflammatory conditions)
Psychotropic medication use within 1 month
Current psychotic symptoms
Autism Spectrum Disorder (ASD)
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How to participate?

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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