Study of Markers of Iron Metabolism and Their Relationship With Phosphocalcic and Hepatic Metabolism and Inflammation in Hemodialysis Patients (MARMEFE)

  • STATUS
    Recruiting
  • End date
    Dec 1, 2031
  • participants needed
    200
  • sponsor
    Ramsay Générale de Santé
Updated on 29 October 2022

Summary

From a scientific point of view and for publication purposes, it therefore seems important to study the metabolism of iron and in particular to define its conditions of absorption, metabolism, elimination and storage in the body at course of advanced renal failure.

The study will follow the evolution of hormones regulating iron metabolism and put into perspective their links with phosphocalcic and hepatic metabolisms as well as inflammation in hemodialysis patients.

The main objective of this program is to study the evolution of hepcidin and erythroferrone levels in hemodialysis patients. These two biomarkers regulating iron metabolism are not performed routinely in dialysis centers and are not listed in the nomenclature.

Details
Condition Iron Metabolism Disorders, Calcium Phosphate Metabolism, Hepatic Metabolic Disorders, Hemodialysis Complication
Treatment Blood test
Clinical Study IdentifierNCT05586867
SponsorRamsay Générale de Santé
Last Modified on29 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Adult dialysis patient
Patient able to understand the information necessary for the study and having signed his written consent to participate
Affiliated patient or beneficiary of a social security scheme

Exclusion Criteria

Medically unstable or frail patient
Patient with hemoglobin less than 7g/dl
Patient with HIV+ or AIDS, patient with replicating hepatitis B or C
Patient participating in another clinical study requiring an additional blood sample
Patient benefiting from legal protection measures (guardianship, guardianship, etc.) adult under guardianship, guardianship or other legal protection, deprived of freedom by judicial or administrative decision
Pregnant, breastfeeding or parturient woman
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