Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up. (DONATE)

  • STATUS
    Recruiting
  • days left to enroll
    79
  • participants needed
    90
  • sponsor
    Indiana University
Updated on 17 October 2022
ct scan
Accepts healthy volunteers

Summary

We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a history of kidney stones.

Description

Indiana University Health center has a large nephrology and transplant service which is well versed in taking care of kidney donors with history of kidney stones. We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a history of kidney stones. In this study we are contacting past kidney donors and participants with kidney stone who were declined as kidney donors. We will use blood tests, 24-hour urine tests, computed tomography (CT) scan, patient reported medical history and medical history in the patient's chart to gather data. This data will help us compare non stone donors, stone donors, and participants with kidney stone who were declined as kidney donors.

Details
Condition Kidney Stones
Treatment Blood draw, 24 hour urine collection, low dose radiation abdomen/pelvis CT scan (stone protocol)
Clinical Study IdentifierNCT05519150
SponsorIndiana University
Last Modified on17 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Age > 18
Evaluation for kidney donation > 2 years ago, with A) no history of kidney stones, or kidney stones on Imaging and successfully donated a kidney B) either had history of kidney stones or kidney stones on imaging and either i) successfully donated a kidney or ii) were declined for donation due to history of kidney stones, Litholink abnormalities or Imaging findings
Willing to participate and sign an informed consent

Exclusion Criteria

Subjects who are currently pregnant or breast feeding
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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