Efficacy of the Transversus Abdominis Plane Block (TAP-Block) on Analgesia After Cephalic Duodeno-pancreatectomy (TAP-Block)

  • End date
    May 29, 2023
  • participants needed
  • sponsor
    University Hospital, Strasbourg, France
Updated on 17 October 2022


Pancreatic duodenectomy is one of the treatments offered to patients with neoplastic disease of the pancreas. In France, in 2018, 14,000 duodeno-pancreatectomies were performed, including 140 at the Hautepierre hospital at the Strasbourg University Hospital. Pancreaticoduodenectomy is a major surgery, causing significant postoperative pain that should be minimized through multimodal analgesia involving in particular locoregional anesthesia. Since 2019, the recommendations of the ERAS company concerning ERAS (Improved Rehabilitation After Surgery) after pancreaticoduodenectomy recommend the establishment of thoracic epidural analgesia in order to limit postoperative pain. When there is a contraindication to the placement of a thoracic epidural, in particular due to arterial and/or venous vascular reconstructions requiring potential perioperative curative anticoagulation, the administration of local anesthetic by pericatricial catheter is recommended. recommended. The Transversus Abdominis Plane (TAP) block has proven analgesic efficacy, safety and harmlessness in colorectal surgery.

Condition Pancreatic Neoplasms
Clinical Study IdentifierNCT05546970
SponsorUniversity Hospital, Strasbourg, France
Last Modified on17 October 2022


Yes No Not Sure

Inclusion Criteria

Major subject (≥18 years of age)
Subject operated at HUS for cephalic duodeno-pancreatectomy between 01/01/2018 and 01/04/ 2022
Subject who has not expressed an objection to the reuse of their data for scientific research purposes

Exclusion Criteria

Subject having expressed his/her opposition to participate in the study
Admission in intensive care unit after the operation
Morphine treatment at home
Drug addiction, weaned or not
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