Trigeminal Nerve Cardiac Reflex During Resection of Cerebellopontine Angle Tumors and Postoperative Myocardial Injury: a Prospective Cohort Study

  • End date
    Dec 31, 2024
  • participants needed
  • sponsor
    Beijing Tiantan Hospital
Updated on 25 October 2022


Myocardial injury after noncardiac surgery is significantly related to postoperative 30-day mortality. Trigeminal cardiac reflex is one of the main causes of perioperative cardiac emergency. Therefore, the investigators' aim is to test the hypothesis that trigeminal cardiac reflex associates postoperative myocardial damage in participants undergoing cerebellopontine angle tumor surgery. The investigators will observe the association between trigeminal cardiac reflex and myocardial injury by measuring the concentration of plasma high sensitivity cardiac troponin (hs-cTnT) in participants after cerebellopontine angle tumor surgery.

Condition Myocardial Injury, Trigeminal Cardiac Reflex
Treatment Trigeminal cardiac reflex, Trigeminal cardiac reflex, Non-trigeminal cardiac reflex
Clinical Study IdentifierNCT05198648
SponsorBeijing Tiantan Hospital
Last Modified on25 October 2022


Yes No Not Sure

Inclusion Criteria

Patients undergoing elective cerebellopontine angle tumor surgery
Age ≥ 18 years old
ASA class I to III
All those who sign the informed consent form

Exclusion Criteria

Patients with severe heart disease (including patients with preoperative heart rate < 50 beats / min, severe arrhythmias, such as premature beats, paroxysmal supraventricular tachycardia, atrial flutter or fibrillation, patients with myocardial ischemia < 6 months, heart failure, myocarditis, pericarditis or cardiomyopathy)
Patients unable to complete preoperative cardiac assessment
Patients with chronic kidney disease
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