A Combined Endoscopy and Radiology-guided Radiofrequency Ablation Therapy Protocol for Inoperable Perihilar Cholangiocarcinoma (COMBO-RFA)
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- STATUS
- Recruiting
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- End date
- Dec 31, 2024
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- participants needed
- 30
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- sponsor
- Clinical Hospital Colentina
Summary
This prospective clinical trial aims to assess the feasibility, efficacy, and safety of a personalized radiofrequency ablation protocol coupled with complete biliary drainage for patients presenting with inoperable perihilar cholangiocarcinoma.
Description
This clinical trial proposes a personalized treatment approach to inoperable perihilar cholangiocarcinoma consisting of endoluminal ablative therapy via radiofrequency ablation followed by endoscopic biliary drainage.
The main study objectives are:
- To assess the technical feasibility of implementing the proposed therapeutic protocol involving a combined endoscopic-radiologic approach to drainage and ablation
- To evaluate the efficacy of radiofrequency ablation in local disease control
- To evaluate whether complete drainage and radiofrequency ablation have a cumulative benefit in patients with inoperable perihilar cholangiocarcinoma
- To evaluate the safety of our proposed therapeutic protocol combining interventional endoscopy with radiology
Details
| Condition | Perihilar Cholangiocarcinoma |
|---|---|
| Treatment | Endoscopic Biliary Stenting, Endoluminal radiofrequency ablation |
| Clinical Study Identifier | NCT05563870 |
| Sponsor | Clinical Hospital Colentina |
| Last Modified on | 20 October 2022 |
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