The Follow-up Automatically vs. As-Needed Comparison Trial (FAAN-C)

  • End date
    Feb 28, 2028
  • participants needed
  • sponsor
    University of Utah
Updated on 27 October 2022
acute gastroenteritis


Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.



Automatic post-hospitalization follow-up visits are commonly recommended by hospital-based pediatricians. The intuitive appeal of automatic follow-up visits is that they might decrease hospital readmissions and promote continuity of care. However, automatic follow-up visits result in missed work for parents, missed school for children, and expenses like co-pays and transportation costs. The principal alternative strategy to automatic follow-up is PRN (pro re nata, "as-needed") follow-up, a patient and family-centered approach that empowers parents to monitor their child's symptoms and decide if a follow-up visit is necessary.


Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.


The Follow-up Automatically vs As-Needed Comparison (FAAN-C, or "fancy") trial is a multicenter randomized controlled trial


Children hospitalized for pneumonia, skin and soft tissue infection, acute gastroenteritis, or urinary tract infection will be eligible for enrollment.


Randomization to a recommendation for PRN post-hospitalization follow-up


Randomization to a recommendation for automatic post-hospitalization follow-up


The primary outcome is hospital readmission within 14 days of discharge. Secondary outcomes are medical interventions and child health-related quality of life. Exploratory outcomes are cost burden, child time, parent time, symptom duration, total additional ambulatory visits, non-primary care ambulatory visits, parent self-efficacy, parent anxiety, satisfaction with care, telephone and electronic communications with medical providers, well-child visits, immunizations, usual place of medical care, and medical interventions related to the index infection. Safety outcomes are medical errors and hospital readmissions related to the index infection.


A total of 2,674 patients (1,337 patients in each group) will be randomized, providing 90% power to demonstrate non-inferiority of a recommendation for PRN follow-up compared to a recommendation for automatic follow-up.

Condition Pneumonia, Urinary Tract Infections, Soft Tissue Infections, Gastroenteritis
Treatment As-needed follow up, Automatic follow-up
Clinical Study IdentifierNCT05471908
SponsorUniversity of Utah
Last Modified on27 October 2022


Yes No Not Sure

Inclusion Criteria

Age <18 years at the time of randomization
Hospitalization due to a primary diagnosis of pneumonia, skin and soft tissue infection, acute gastroenteritis, or urinary tract infection
Parent speaks English or Spanish

Exclusion Criteria

Presence of a comorbid disease that is both chronic and complex
Principal disease required surgical intervention (beyond superficial incision and drainage)
A well-child check-up or post-hospitalization follow-up visit is already scheduled within 7 days of hospital discharge
Parent or participant strongly prefers PRN or automatic follow-up
A medical provider feels strongly that a post-hospitalization follow-up visit is needed within 7 days of hospital discharge
Sibling concurrently hospitalized
Unable to identify a clinic where the participant would receive any needed post-hospitalization follow-up
Diagnosis of pneumonia complicated by
Receiving a chest tube
Diagnosis of urinary tract infection complicated by
History of neurogenic bladder or urologic surgery
Renal imaging anticipated within 7 days of hospital discharge
Renal abscess
Diagnosis of skin and soft tissue infection complicated by
Chronic wound
Postoperative infection
Predisposition to poor wound healing
Discharging with a drain in place
Complicated by necrotizing fasciitis or toxic shock syndrome
Diagnosis of gastroenteritis complicated by
Hemolytic uremic syndrome
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