Perio Treatment & Cerebrovascular Function

  • End date
    Sep 20, 2023
  • participants needed
  • sponsor
    University of Santiago de Compostela
Updated on 4 October 2022
root planing
periodontal surgery
periodontal treatment
severe periodontal disease
Accepts healthy volunteers


Periodontitis has been linked to increased risk of cerebrovascular disease. Impaired brain hemodynamics has been suggested as early markers of cerebral macro and microangiopathy. Therefore, the aim of this clinical trial will be to assess the potential effect of periodontal treatment on cerebral hemodynamics in otherwise healthy patients with severe periodontitis over 6 months.

Condition Periodontitis
Treatment Periodontal treatment
Clinical Study IdentifierNCT05506917
SponsorUniversity of Santiago de Compostela
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Otherwise healthy subjects with severe periodontitis

Exclusion Criteria

<10 teeth
current smokers
undergo periodontal treatment within the last 6 months
receive antibiotics or anti-inflammatory drugs within the last 3 months
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