Atrial Fibrillation in Beta-Thalassemia

  • End date
    Jul 1, 2032
  • participants needed
  • sponsor
    University Hospital of Ferrara
Updated on 7 October 2022


The study aims to evaluate the clinical, laboratory and instrumental differences that exist between beta-thalassemia patients with atrial fibrillation and those not affected by arrhythmia.


Observational, retrospective and prospective, single-center study, which involves the collection of clinical, laboratory, electrocardiographic and imaging data of patients with major or intermediate thalassemia who have performed, from 2012 to 2022, or will perform in the next 10 years, a cardiological evaluation at the Cardiology Unit of the University Hospital of Ferrara. Patients will be divided into two groups: thalassemia patients with atrial fibrillation (paroxysmal, persistent or permanent) and thalassemia patients with no history of atrial fibrillation.

The objective of the study is to evaluate whether there is a different prevalence of the characteristics analyzed among these patient populations.

Condition Atrial Fibrillation, Thalassemia
Clinical Study IdentifierNCT05508932
SponsorUniversity Hospital of Ferrara
Last Modified on7 October 2022


Yes No Not Sure

Inclusion Criteria

Transfusion-dependent Beta-thalassemia
Follow-Up at the Cardiology Unit of the University Hospital of Ferrara
Electrocardiogram performed
Echocardiogram performed

Exclusion Criteria

Age <18 years
State Of pregnancy
Inability to give informed consent
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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