Efficacy and Safety of Astragalus for Non-motor Symptoms of Parkinsonism

  • STATUS
    Recruiting
  • End date
    Jun 1, 2024
  • participants needed
    60
  • sponsor
    Fujian Medical University Union Hospital
Updated on 7 October 2022

Summary

Parkinsonism is a cluster of neurodegenerative disease with motor and non-motor symptom. However, there is still a lack of research on the treatment for non-motor symptoms of Parkinsonism, especially autonomic dysfunctions such as orthostatic hypotension. Efficacy and safety of astragalus for non-motor symptoms of Parkinsonism will be assessed by an open-label self-controlled before-and-after study.

Details
Condition Parkinsonism
Treatment Physical therapy group, Astragalus
Clinical Study IdentifierNCT05506891
SponsorFujian Medical University Union Hospital
Last Modified on7 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Participants with a clinical diagnosis of primary Parkinsonism and orthostatic hypotension
Adults signed informed consents

Exclusion Criteria

Patients with history of astragalus allergy
Patients with secondary Parkinsonism that cannot be excluded
Patients with diseases that may cause other types of hypotension or similar symptoms/signs because of hypotension
Patients with other medical conditions requiring treatments that may affect blood pressure
Patients with other neurological disorders
Patients with serious comorbidities and immune diseases
Uncooperative patients
Pregnant or lactating women
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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