Establishment and Application of a New Imaging System for Otology Based on Ultra-high Resolution CT

  • End date
    Dec 14, 2024
  • participants needed
  • sponsor
    Beijing Friendship Hospital
Updated on 7 October 2022
hard of hearing
peripheral vertigo
Accepts healthy volunteers


Tinnitus, hearing loss and vertigo are the three major diseases of otology, affecting hundreds of millions of people in our country, and are major health problems. Ear structures and lesions are deeply embedded in the bone, and CT is the preferred examination technique. The key structures of the ear are small and the lesions are hidden. Spiral CT is "not visible" and "undiagnosed" due to insufficient spatial resolution. The ultra-high-resolution CT independently developed by our team has a spatial resolution of 50 μm, which is 6 times higher than that of high-end spiral CT, and solves the problem of "not showing" ear diseases. However, with the transformation of imaging modes and the improvement of display capabilities, the imaging system of helical CT is no longer applicable. It is urgent to carry out systematic research to create matching imaging plans, imaging anatomy standards and disease assessment standards to solve the problem of "undiagnosed". problem. This project plans to build an adult and pediatric imaging solution based on ultra-high-resolution CT to optimize image quality and radiation dose; comprehensively evaluate conduction, sensory, and surgical-related fine structures of the ear, and establish a new 0.1mm-scale image anatomy atlas; A prospective study conducted by the center analyzes the hidden pathological changes of tinnitus, deafness and vertigo, evaluates the diagnostic efficacy of ultra-high-resolution CT for the above diseases, and establishes new diagnostic criteria for lesion detection, symptom correlation, and efficacy evaluation. This project will bring new changes to the practice of otology clinical diagnosis and treatment

Condition Hearing Loss, Tinnitus, Vertigo
Treatment ultra-high-resolution computed tomography exams
Clinical Study IdentifierNCT05533840
SponsorBeijing Friendship Hospital
Last Modified on7 October 2022


Yes No Not Sure

Inclusion Criteria

Due to tinnitus/deafness/peripheral vertigo/peripheral facial paralysis in the ENT department of our hospital
Meet the ethical requirements of U-HRCT examination
Can cooperate with the completion of U-HRCT examination
Surgery in the ENT department of our hospital
At least one follow-up or re-examination after discharge

Exclusion Criteria

History of previous ear surgery and trauma
CT image artifacts or incomplete scanning coverage
Incomplete clinical data
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