Immunohistochemical Study of Neurodegenerative Diseases

  • End date
    Apr 30, 2023
  • participants needed
  • sponsor
    First Affiliated Hospital of Zhejiang University
Updated on 7 October 2022
alzheimer's disease
neurodegenerative disorder
Accepts healthy volunteers


The subject uses cytof to analyze PBMC of sporadic AD and DLB, which is used to reveal the differences in immune characteristics of the two diseases at the single-cell level, build immune models for specific diseases, and define these two neurodegenerative diseases with high precision from the level of molecular immunity. To provide basis for further study of the immunohistochemical differences between the two diseases, and provide objective support for clinical diagnosis and differential diagnosis.

Condition Alzheimer Disease, Lewy Body Disease, Neurodegenerative Diseases
Treatment Detection of cytof in peripheral PBMC, Donepezil for patients with AD and DLB
Clinical Study IdentifierNCT05518409
SponsorFirst Affiliated Hospital of Zhejiang University
Last Modified on7 October 2022


Yes No Not Sure

Inclusion Criteria

AD inclusion criteria
a.Clinical diagnosis of Alzheimer's Disease
DLB inclusion criteria
Clinical diagnosis of Dementia with Lewy bodies

Exclusion Criteria

Infectious diseases
autoimmune disease
heart failure
chronic obstructive pulmonary disease (COPD)
renal failure
recently major surgery
alcohol and / or drug abuse
disturbance of consciousness
clinical diagnosis of major depression disorder
clinical diagnosis of Anxiety disorder
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note