Evaluation of the Effect of Para-sternal Block on Postoperative Respiratory Function After Cardiac Sternotomy Surgery (PARACARD)

  • STATUS
    Recruiting
  • End date
    Oct 14, 2023
  • participants needed
    84
  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 7 October 2022
anesthesia
morphine
ropivacaine
sternotomy

Summary

Postoperative pain after cardiac surgery is associated with reduced postoperative respiratory function. There is an association between greater pain and more pronounced decreases in lung volumes postoperatively. With an incidence of 10% to 25% of cases, pulmonary complications are the second source of postoperative morbidity after cardiac complications; in 2-5% of cases, the dysfunction is severe and leads to significant consequences that can lead to death. It has been shown that postoperative pain after cardiac surgery is associated with a reduction in functional respiratory capacity. There is an association between greater pain and more pronounced decreases in lung volumes postoperatively. The main objective of this study will be to evaluate the impact of locoregional anesthesia by parasternal block analgesic on postoperative respiratory function at D1 postoperatively

Details
Condition Cardiac Surgery, Ultrasound-guided Parasternal Block, Postoperative Pulmonary Complications, Pulmonary Function Testing
Treatment parasternal block, Standard pain management
Clinical Study IdentifierNCT05515809
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on7 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients over 18 years of age
Elective cardiac surgery under CEC with sternotomy
Written informed consent from the patient
Women of childbearing age must have a negative urine HCG pregnancy test

Exclusion Criteria

Thoracotomy approach
Mini-sternotomy approach
Opioid drug dependence or chronic opioid drug use
Chronic benzodiazepine use (respiratory depressant treatment or treatment that may affect postoperative respiratory function)
Contraindication or allergy to local anesthetics
Emergency surgery
Acute infective endocarditis
Immunosuppressive or steroid treatment (prednisone > 0.5mg/kg/day or equivalent)
AIDS with CD4 count <200/mm3
Autoimmune disorder
Transplant recipient
Inclusion in another study within the last 30 days
Pregnancy
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