Inhalation of Sevoflurane Versus Intravenous Midazolam,Ketamine,Propofol For Pediatrics Undergoing Upper GI Endoscopy

  • STATUS
    Recruiting
  • End date
    Dec 30, 2022
  • participants needed
    74
  • sponsor
    Zagazig University
Updated on 11 August 2022

Summary

In the field of pediatric gastroenterology, upper gastrointestinal endoscopy has established itself as a diagnostic and therapeutic tool. In order to increase patient tolerance during this procedure, deep sedation is essential. Children are at a higher risk of serious adverse effects from procedural sedation; thus, their safety is a primary issue throughout this procedure. Multiple studies have been done to find the ideal method for procedural sedation in terms of ease of administration, quality, safety of sedation and recovery profile, but the consensus seems lacking. In this study we will compare between nasal inhalation of sevoflurane versus intravenous ketamine, midazolam and propofol for pediatrics undergoing upper gastrointestinal endoscopy.

Details
Condition Upper GI Bleeding
Treatment Sevoflurane Inhalation Solution, Midazolam, Ketamine and Propofol
Clinical Study IdentifierNCT05474937
SponsorZagazig University
Last Modified on11 August 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

A consent from the parents or 1st degree relative
Both sexes
Pediatric patients aged 1year to 4 years old undergoing
elective upper GI endoscopy
ASA class I &II
BMI between 5th percentile and the 85th percentile (<http://www.kidshealth.org>)

Exclusion Criteria

Hypersensitivity to drugs included in the study
Difficult airway or known airway problems
Active bleeding from esophageal varices
Respiratory and cardiac problems
Neurological disorders
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