Effectiveness of rTMS on Pain and Quality of Life in Patients With Cancer Neuropathic Pain. Clinical Trial.

  • End date
    Jan 30, 2023
  • participants needed
  • sponsor
    Fundacion Universitaria Maria Cano
Updated on 4 October 2022
cancer pain


The purpose of this study is to evaluate the effectiveness of Repetitive transcranial magnetic stimulation (rTMS) on pain and quality of life in patients with cancer neuropathic pain.

Although there are currently different therapeutic options for neuropathic pain, most are limited or restricted to pharmacotherapy. Transcranial magnetic stimulation (TMS) is a tool recently incorporated into neuroscience in the management of neuropathic cancer pain.

The study will include 10 patients with oncologic neuropathic pain who will receive 20 sessions of rTMS and the effect on pain and quality of life.


Neuropathic pain is defined as pain caused by a primary lesion or transient dysfunction of the central or peripheral nervous system. In cancer, it is generated as a consequence of multiple factors such as: direct compression of nerve structures, post-surgical nerve injuries, and nerve injuries secondary to chemotherapy. At least 3.5 million people around the world suffer from this symptom associated with cancer; Of this population, 38% experience pain in all stages and 80% in advanced stages, negatively impacting quality of life.

Condition Neuropathic Pain
Treatment Repetitive transcranial magnetic stimulation
Clinical Study IdentifierNCT05480410
SponsorFundacion Universitaria Maria Cano
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients with neuropathic pain of oncological origin
Patients of legal age (18 years old)
Patients using their cognitive faculties

Exclusion Criteria

History of negative reaction to TMS
History of seizure, history of epilepsy stroke, brain surgery and cranial metal implants
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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