Different Endoscopic Gastric Cancer Risk Assessments

  • End date
    Jul 4, 2025
  • participants needed
  • sponsor
    Yanqing Li
Updated on 4 October 2022


The Kimura-Takamoto classification established in Japan can observe the extent of gastric atrophy in real-time under endoscopy, and diffuse atrophy also indicates an increased risk of gastric cancer. Recent studies have found that the evaluation of intestinal metaplasia score (EGGIM score) of various stomach parts by electronic staining can well identify OLGIM III\ IV patients. Although the Kimura-Takamoto classification and EGGIM score can evaluate the risk of gastric cancer in patients, only in cross-sectional studies, it is not clear the diagnostic value of risk assessment in population screening. Early gastric cancer has the characteristics of hidden lesions and a high rate of clinical missed diagnosis. Concentrating high-risk groups through risk scores is expected to guide endoscopic doctors to conduct a targeted careful examination. However, it is not clear whether Kimura-Takamoto classification and EGGIM score can improve the detection rate of early gastric cancer in clinical practice.

Condition Gastric Cancer Screening
Treatment Kimura-Takemoto classification, EGGIM
Clinical Study IdentifierNCT05458388
SponsorYanqing Li
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients aged 40-80 years undergoing gastroscopy
Patients intend to undergo ESD treatment

Exclusion Criteria

patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy
Patients with previous surgical procedures on the stomach
patients with contraindications to biopsy
Patients who refuse to sign the informed consent form
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