Prone Fluid Responsiveness in Children

  • End date
    Jul 31, 2023
  • participants needed
  • sponsor
    Seoul National University Hospital
Updated on 4 October 2022


In pediatric patients in the prone position, the reliability of pulse pressure variation and stroke volume variation, and pleth variability index to predict fluid responsiveness have not previously been established. Perioperatively, in this setting, optimizing fluid management can be challenging, and fluid overload is associated with both intraoperative and postoperative complications. The investigator designed this study to assess the sensitivity and specificity of baseline PPV, SVV, and PVI the tidal volume (VT) challenge (VTC) and in predicting fluid responsiveness during elective neurosurgery.

Condition Pediatric ALL
Treatment TVC
Clinical Study IdentifierNCT05449886
SponsorSeoul National University Hospital
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

elective neurosurgery and requiring prone positioning

Exclusion Criteria

(1) chronic cardiac arrhythmia; (2) depressed left (<30% of ejection fraction) (3) patients with pulmonary disease
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