A New Prognostic Stratification-based Safety and Efficacy Study of Ruxolitinib in Myelofibrosis

  • End date
    Dec 10, 2023
  • participants needed
  • sponsor
    Qilu Hospital of Shandong University
Updated on 4 October 2022


This is a multi-center, prospective, single-arm study to assess safety and efficacy of Ruxolitinib in myelofibrosis (MF) based on a new prognostic stratification.

Condition Myelofibrosis
Treatment Ruxolitinib
Clinical Study IdentifierNCT05447260
SponsorQilu Hospital of Shandong University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Male or female patients aged ≥18 years with a diagnosis of primary or secondary MF by World Health Organization and International Working Group for Myeloproliferative Neoplasms Research and Treat- ment (IWG-MRT) criteria
Received ruxolitinib treatment for ≥3 months

Exclusion Criteria

Malignant tumors with other progression or myelofibrosis secondary to other diseases
Exclude myelofibrosis patients after splenectomy
Patients with poor compliance with case follow-up or lost to follow-up
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