A New Prognostic Stratification-based Safety and Efficacy Study of Ruxolitinib in Myelofibrosis

  • STATUS
    Recruiting
  • End date
    Dec 10, 2023
  • participants needed
    87
  • sponsor
    Qilu Hospital of Shandong University
Updated on 4 October 2022

Summary

This is a multi-center, prospective, single-arm study to assess safety and efficacy of Ruxolitinib in myelofibrosis (MF) based on a new prognostic stratification.

Details
Condition Myelofibrosis
Treatment Ruxolitinib
Clinical Study IdentifierNCT05447260
SponsorQilu Hospital of Shandong University
Last Modified on4 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Male or female patients aged ≥18 years with a diagnosis of primary or secondary MF by World Health Organization and International Working Group for Myeloproliferative Neoplasms Research and Treat- ment (IWG-MRT) criteria
Received ruxolitinib treatment for ≥3 months

Exclusion Criteria

Malignant tumors with other progression or myelofibrosis secondary to other diseases
Exclude myelofibrosis patients after splenectomy
Patients with poor compliance with case follow-up or lost to follow-up
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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